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The inclusion of a dye to help enhance the visualization of the formulation or composition when applied, and the ability to visually inspect the location of the formulation or composition after administration without further intervention, represents an advance over currently available methods for testing intratympanic therapeutics in animal models and/or human trials

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LTF can also be hydrolyzed to form a number of smaller AMPs such as lactoferricin and lactoferrampin that display similar or even higher antibacterial activity than the full polypeptide (Gruden and Poklar, 2021)

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For example, week 5 can range from 18 to over 7,000